Archive

Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice

29.12.2010

The heart of leptin-deficient ob/ob mice is characterized by pathologic left ventricular hypertrophy along with elevated triglyceride (TG) content, increased stearoyl-CoA desaturase (SCD) activity, and increased myocyte apoptosis. In the present study, using an ob/ob;SCD1-/- mouse model, we tested the hypothesis that lack of SCD1 could improve steatosis and left ventricle (LV) function in leptin deficiency. We show that disruption of the SCD1 gene improves cardiac function in ob/ob mice by ...

Local injection of MK801 modifies oscillatory activity in the nucleus accumbens in awake rats

29.12.2010

Oscillatory activity of the electrical potentials recorded in the brain is believed to be essential for the proper processing of information. In recent years, high frequency oscillations (HFO ...

Scientists from the Nencki Institute co-author a paper published in the Science* magazine explaining one of the secrets of cancer formation.

22.12.2010

The paper appeared in the Science Express category, which is the editors-in-chief’s selection of the best works published in the Science magazine.

The paper entitled “PML ...

First session of the Council of National Centre for Science

22.12.2010

Leszek Kaczmarek, M.Sc. 1981, Warsaw University (Biochemistry/Molecular Biology); Ph.D. 1983, Cell Biology/Experimental Hematology (supervisor: W.Wiktor-Jedrzejczak); D.Sc. (Dr. hab.) 1988, ...

EMBO Installation Grant

17.12.2010

The award is financed within the EMBO Young Investigator Programme. It is a significant achievement for both Dr Wilanowski and the Nencki Institute as Dr Wilanowski was selected as one of only ...