Patent Category: Therapies

Small-molecule inhibitors of GRHL transcription factors for use in cancer treatment, especially colorectal cancer

23.09.2022

The subject of the patent application are compounds that inhibit transcription factors from the Grainyhead-like (GRHL) family, especially GRHL2, as well as the use of these compounds in the treatment of diseases dependent on the functioning of this protein, in particular in the treatment of cancer. Nencki Institute is the co-applicant with University of Warsaw and National Medicines Institutes. University of Warsaw is the leader in patent protection and commercialization-related ...

Nitroxyl derivative of polyphenol, methods of its production and its application

12.07.2022

The subject of the patent application is a nitroxyl derivative of polyphenol with the formula: Q-(L-A)n, where Q denotes a group derived from polyphenol; L denotes an ester linking group ...

Engineered synthetic peptides, compositions containing them, and methods of their use in the treatment of malignant gliomas

07.06.2022

The invention concerns synthetic peptides, compositions and methods of use for treating tumors infiltrated with macrophages, such as glioblastomas. Peptides target osteopontin (SPP1, OPN) ...

Inhibitor of protein kinase D (PKD) for use in prevention or treatment of obesity and a pharmaceutical composition for such use

03.03.2021

Description of the invention will be available after the patent application is published. The Nencki Institute is a co-applicant of the patent with University of Würzburg. For more ...

Dicarboximide derivative for use in the treatment of cancer

01.03.2021

Description of the invention will be available after the patent application is published. The Nencki Institute is a co-applicant of the patent with Centre of Molecular and Macromolecular ...