Patent Category: Therapies

Use of epigenetic inhibitor 1-(β-D-ribofuranosyol)-2(1H)-pyrimidinone (zebularine) for promoting wound healing, complex tissue and organ regeneration

In one aspect, the present invention provides a composition comprising zebularine, a nucleotide inhibitor of DNA methyltransferase, optionally in combination with retinoic acid, and said composition for use in promoting complex tissue regeneration and wound healing in a subject. In another aspect the present invention provides zebularine as a therapeutic agent, optionally in combination with retinoic acid, for use in promoting regeneration and healing of wounds resulting from mechanical ...