Flow cytometry
DNA damage analysis

High-throughput cytometric detection of the H2AX histone phosphorylation, which is a sensitive marker of DNA damage, especially double-strand breaks (DSBs). It is possible to correlate γH2AX phosphorylation with the cell cycle phase and/or apoptosis initiation. This approach provides a more complete picture of the cellular processes occurring during drug treatment or UV exposure.


Milena Wiech, PhD

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