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Tubulin binding protein, CacyBP/SIP, induces actin polymerization and may link actin and tubulin cytoskeletons

Cytoskeleton, which is built by three types of structural elements: microtubules, intermediate filaments and actin filaments, provides mechanical strength to a cell and plays an active role in many processes, including cell motility, intracellular transport and signal transduction. Impaired organization of the actin cytoskeleton may be the cause of many diseases. For example, in cancerous cells perturbations in actin polymerization/depolymerization result in higher cell motility and ...