Patent Category: Research Tool

Methods for delivering biologically active molecules into cells

01.09.2020

The invention concerns methods for delivering a biologically active molecule into a cell by linking a molecule to the cell surface, wherein the molecule can act as a surface receptor, then complexing the biologically active molecule with a ligand for the surface receptor, and finally contacting the biologically active molecule-ligand complex with the cell surface are disclosed. Delivery of any biologically active molecule, e.g. proteins, enzymes, nucleic acids, hormones, nucleic acids, and ...

Modified expression vectors, Fusion proteins, their composition and use of thereof

01.09.2020

A subject of the invention is a replication-expressing vector. Further, a subject of the invention is a PhoA-His6-polysignal protein TSRGDHELLGGGAAPVGG_10 fusion protein comprising the vector ...

Genetically coded FRET-based biosensor of MMP-9 activity and its application

01.09.2020

The present invention relates to a genetically encoded FRET-based biosensor to monitor the activity of matrix metalloproteinase 9 (MMP-9). MMP-9 is an extracellular acting endopeptidase ...

A method and a system for segmenting a 3D image comprising round objects

01.09.2020

The invention concerns a computer-implemented method for segmenting a 3D image comprising round objects, the method comprising the steps of dividing the 3D image into 2D slice images, for each ...

Biological system and assay for identifying modulators of tubulin ligases

01.09.2020

Tetrahymena used as a host cell in a biological assay for identification of modulators of tubulin ligases. The inventor associated with the Nencki Institute is Prof. Dorota Włoga. For more ...