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Discovery of a novel family of putative oxidoreductases implicated in tumor developement

Although the sequence of the human genome has been known for ten years, still the molecular function of a considerable part of the human proteome (at least a quarter of all the human proteins) remains uknown. Such proteins, even if circumstantial links to human disease exist, cannot be used in building novel therapeutic hypotheses. On the other hand, if there are no hypotheses regarding the molecular function of a gene and protein, it seldom becomes to subject of detailed investigations.Read more...