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Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications

08.09.2010

Subependymal giant cell astrocytomas (SEGAs) are rare brain tumors observed in 10-20% of patients with tuberous sclerosis complex (TSC) and are the major cause of morbidity in children and young adults with TSC. A disease is caused by mutations in one of two tumor suppressor genes TSC1 or TSC2, which result in enhancement of mTOR kinase activity, dysregulation of cell growth, abnormal differentiation and tumorigenesis. Signaling via mTOR participates in multifaceted cellular and genomic ...

Laureate of the “Homing Plus” programme of the Foundation for Polish Science

11.08.2010

One of them was Dr. Krishendu Ganguly from the Nencki Institute of Experimental Biology PAS, Laboratory of Molecular Neurobiology, headed by Prof. Leszek Kaczmarek. Dr. Ganguly was awarded nearly ...

The Nencki Award 2008

06.08.2010

It is my very great pleasure to introduce the laureate of the First Edition of the Nencki Award. The Award was established by The Scientific Council of the Nencki Institute of Experimental ...

The Nencki Award 2010

06.08.2010

Ernesto Carafoli, born in Italy in 1932, received his M.D. degree (1957) from the University of Modena and later his habilitation in general pathology (1965) and biochemistry (1968). In the 1960s ...

New Laboratory at the Nencki Institute

03.08.2010

Dr. Piwocka’s lab will provide core-facility services, high quality expertise and training in flow cytometry for in-house and outside investigators. It will also be involved in research and ...