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CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release

03.02.2014

Endocannabinoid signaling has been implicated in modulating insulin release from ß cells of the endocrine pancreas. ß Cells express CB1 cannabinoid receptors (CB1Rs), and the enzymatic machinery regulating anandamide and 2-arachidonoylglycerol bioavailability. However, the molecular cascade coupling agonist-induced cannabinoid receptor activation to insulin release remains unknown. By combining molecular pharmacology and genetic tools in INS-1E cells and in vivo, we show that CB1R ...

Stwardnienie rozsiane patogeneza i jak można pomóc

31.01.2014

Beyond making experiments: an advice on how to become a good scientist and stay motivated in science

31.01.2014

Neuroimaging of the human brain in LOBI – what can we measure?

31.01.2014

Award for the Nencki Institute: Populariser of Science 2013

31.01.2014

Prof. Adam Szewczyk, the Director of the Institute, accepted the award and the Diploma from the hands of prof. Michał Kleiber, the president of PAN (The Polish Academy of Sciences) and the ...