The Mirava Polyscope is an advanced microscopy system that integrates confocal imaging, MATRIX, STED, and MINFLUX into a single instrument, enabling observations from the micrometer scale down to single‑molecule resolution (~3 nm). With multiple imaging modes and modules that enhance image quality, the system allows flexible adaptation of the method to the sample from live cells and thick tissues to precise nanostructure analysis. It offers high sensitivity, gentle illumination, and seamless switching between techniques, significantly expanding the range of possible experiments and accelerating the acquisition of reliable results.