Patent Category: Therapies

Inhibitors of interactions between TRF1-TIN2 or TRF2-TIN2 telomeric proteins for use in anticancer therapy

The present invention relates to a novel compounds for use in treatment or prevention of cancer, in particular to use of said compounds as an inhibitors of interactions between TRF1-TIN2 or TRF2-TIN2 telomeric proteins. Due to the fact that telomerase is reactivated in most cancerous cells it became a promising target for anticancer chemotherapy. However, despite the fact that telomeres of cancerous cells are usually shorter than telomeres of surrounding cells, decreasing of telomere ...

Bile acid derivatives and use thereof

A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.