Patent Category: Therapies
Small-molecule inhibitors of GRHL transcription factors for use in cancer treatment, especially colorectal cancer
Nitroxyl derivative of polyphenol, methods of its production and its application
12.07.2022
The subject of the patent application is a nitroxyl derivative of polyphenol with the formula: Q-(L-A)n, where Q denotes a group derived from polyphenol; L denotes an ester linking group ...Engineered synthetic peptides, compositions containing them, and methods of their use in the treatment of malignant gliomas
07.06.2022
The invention concerns synthetic peptides, compositions and methods of use for treating tumors infiltrated with macrophages, such as glioblastomas. Peptides target osteopontin (SPP1, OPN) ...Inhibitor of protein kinase D (PKD) for use in prevention or treatment of obesity and a pharmaceutical composition for such use
03.03.2021
The invention relates to a PKD protein kinase inhibitor for use in preventing or treating obesity in a subject, including preferably also related conditions such as diabetes, wherein the PKD ...Dicarboximide derivative for use in the treatment of cancer
01.03.2021
The subject of the invention is the BK124.1 compound of Formula I, for use in the treatment of cancer, wherein the cancer is leukemia or another cancer characterized by a clonal increase in the ...