The present invention is directed to isolated peptides, compositions comprising same and methods of use thereof for treating tumors infiltrated with macrophages, such as glioblastomas.
A description of the invention will be available after the patent application is published. Nencki Institute is the co-applicant with International Institute of Molecular and Cell Biology in Warsaw and Maj Institute of Pharmacology Polish Academy of Sciences. International Institute of Molecular and Cell Biology in Warsaw is the leader in patent protection and commercialization-related activities. For more information contact Technology Transfer Office.
A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.
A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.
A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.
A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.
The subject of the patent application are compounds that inhibit transcription factors from the Grainyhead-like (GRHL) family, especially GRHL2, as well as the use of these compounds in the treatment of diseases dependent on the functioning of this protein, in particular in the treatment of cancer. Nencki Institute is the co-applicant with University of Warsaw and National Medicines Institutes. University of Warsaw is the leader in patent protection and commercialization-related activities. For more information contact Technology Transfer Office.
The subject of the patent application is a nitroxyl derivative of polyphenol with the formula: Q-(L-A)n, where Q denotes a group derived from polyphenol; L denotes an ester linking group containing 1 to 3 carbon atoms; A denotes a 5- or 6-membered heterocyclic group containing one nitrogen atom in the form of a nitroxyl radical (NO•), in which both carbon atoms adjacent to the nitroxyl radical are independently substituted by one or two C1-C3 alkyl groups; and n denotes an integer from 1 to 5. The subject of the application also includes methods for obtaining the above-mentioned derivative and its use as an antioxidant, especially an anti-aging agent. Nencki Institute is the co-applicant with University of Warsaw. University of Warsaw is the leader in patent protection and commercialization-related activities. For more information contact Technology Transfer Office.
A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.