Patent Category: Therapies

Compositions and methods for treating glioma

26.08.2025

The present invention is directed to isolated peptides, compositions comprising same and methods of use thereof for treating tumors infiltrated with macrophages, such as glioblastomas. Malignant gliomas account for about 80% of primary brain tumors in adults. The most frequent and malignant is glioblastoma (GBM, WHO grade IV), a very aggressive, highly diffusive brain tumor, which due to a late diagnosis and the lack of efficient therapy remains incurable. The current management of ...

Bile acid derivatives and use thereof

20.08.2025

A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.

Bile acid for use in the prevention or treatment of inflammatory diseases of the respiratory system

20.08.2025

A description of the invention will be available after the patent application is published. Nencki Institute is the sole applicant. For more information contact Technology Transfer Office.

Small-molecule inhibitors of GRHL transcription factors for use in cancer treatment, especially colorectal cancer

23.09.2022

The subject of the patent application are compounds that inhibit transcription factors from the Grainyhead-like (GRHL) family, especially GRHL2, as well as the use of these compounds in the ...

Nitroxyl derivative of polyphenol, methods of its production and its application

12.07.2022

The subject of the patent application is a nitroxyl derivative of polyphenol with the formula: Q-(L-A)n, where Q denotes a group derived from polyphenol; L denotes an ester linking group ...