Publications

Activity-Dependent Local Translation of Matrix Metalloproteinase-9

28.01.2013

Local, synaptic synthesis of new proteins in response to neuronal stimulation plays a key role in regulation of synaptic morphogenesis. Recent studies indicate that matrix metalloproteinase-9 (MMP-9), an endopeptidase that regulates the pericellular environment through cleavage of its protein components, plays a critical role in regulation of spine morphology and synaptic plasticity. Here, we sought to determine whether MMP-9 mRNA is transported to dendrites for local translation and ...

Curcumin induces permanent growth arrest of human colon cancer cells: Link between senescence and autophagy

06.11.2012

Curcumin, a natural polyphenol derived from the rhizome of Curcuma longa, is a potent anticancer agent, which restricts tumor cells growth both in vitro and in vivo. Thus far curcumin was shown ...

Cognitive function in elderly can be ameliorated by training in temporal information processing

31.10.2012

The study conducted in Laboratory of Neuropsychology by E. Szelag and J. Skolimowska shows for the first time significant benefits of temporal training on broad aspects of cognitive function in ...

Comment on van den Brand et al (2012): voluntary control, yes; of locomotion, probably not

30.10.2012

Using rats trained and tested in an upright posture, Gregoire Courtine and colleagues claim voluntary control of locomotion is restored after paralyzing spinal cord injury. In our polemical ...

Experience-dependent plasticity of the barrel cortex in mice observed with 2-DG brain mapping and c-Fos: effects of MMP-9 KO

30.10.2012

Modifications of properties of the adult sensory cortex by elimination of sensory input (deprivation) serves as a model for studying plasticity in the adult brain. We studied the effects of ...