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Signal Transducer and Activator of Transcription 1 (Stat1) Maintains Basal mRNA Expression of Pro-Survival Stat3-Target Genes in Glioma C6 Cells

The STAT family of transcription factors has 6 members, participating in signal transduction from cytokine and growth factor receptors to the cell nucleus. In many cancers STAT3 plays a key role in transducing the signals stimulating proliferation and viability, whereas STAT1 participates in the inflammatory response, with potential anti-tumour effects. Possibility of selectively inhibiting STAT3 activity is intensely studied, as a possible anti-cancer strategy. However, the role of a ...

Guests at the Nencki Institute

Young people have a chance to learn the basics of magnetic resonance, find out if they can read in mind, learn the process of creating images in a variety of microscopes and become familiar with ...